Hydrophilic Interaction Liquid Chromatography-Electrospray Ionization Mass Spectrometry for Therapeutic Drug Monitoring of Metformin and Rosuvastatin in Human Plasma

In this work a hydrophilic interaction liquid chromatography/positive ion electrospray mass spectrometric assay (HILIC/ESI-MS) has been developed and fully validated for the quantitation of metformin and rosuvastatin in human plasma. Sample preparation involved the use of 100 μL of human plasma, fol...

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Detalles Bibliográficos
Autores principales: Antonopoulos, Nikolaos, Machairas, Giorgos, Migias, George, Vonaparti, Ariadni, Brakoulia, Vasiliki, Pistos, Constantinos, Gennimata, Dimitra, Panderi, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100608/
https://www.ncbi.nlm.nih.gov/pubmed/29954074
http://dx.doi.org/10.3390/molecules23071548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100608/
https://www.ncbi.nlm.nih.gov/pubmed/29954074
http://dx.doi.org/10.3390/molecules23071548

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