A 3D-QSAR Study on the Antitrypanosomal and Cytotoxic Activities of Steroid Alkaloids by Comparative Molecular Field Analysis

As part of our research for new leads against human African trypanosomiasis (HAT), we report on a 3D-QSAR study for antitrypanosomal activity and cytotoxicity of aminosteroid-type alkaloids recently isolated from the African medicinal plant Holarrhena africana A. DC. (Apocynaceae), some of which are...

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Detalles Bibliográficos
Autores principales: Nnadi, Charles Okeke, Althaus, Julia Barbara, Nwodo, Ngozi Justina, Schmidt, Thomas Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100617/
https://www.ncbi.nlm.nih.gov/pubmed/29738470
http://dx.doi.org/10.3390/molecules23051113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100617/
https://www.ncbi.nlm.nih.gov/pubmed/29738470
http://dx.doi.org/10.3390/molecules23051113

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