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Rapid, simple, and clinically applicable high-performance liquid chromatography method for clinical determination of plasma colistin concentrations

BACKGROUND: Since both the antibacterial effects and common adverse effects of colistin are concentration-dependent, determination of the most appropriate dosage regimen and administration method for colistin therapy is essential to ensure its efficacy and safety. We aimed to establish a rapid and s...

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Detalles Bibliográficos
Autores principales: Hanai, Yuki, Matsuo, Kazuhiro, Kosugi, Takayoshi, Kusano, Ayumu, Ohashi, Hayato, Kimura, Itsuki, Hirayama, Shinobu, Nanjo, Yuta, Ishii, Yoshikazu, Sato, Takahiro, Miyazaki, Taito, Nishizawa, Kenji, Yoshio, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100703/
https://www.ncbi.nlm.nih.gov/pubmed/30151222
http://dx.doi.org/10.1186/s40780-018-0119-x