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Proteome‐wide analysis of phospho‐regulated PDZ domain interactions

A key function of reversible protein phosphorylation is to regulate protein–protein interactions, many of which involve short linear motifs (3–12 amino acids). Motif‐based interactions are difficult to capture because of their often low‐to‐moderate affinities. Here, we describe phosphomimetic proteo...

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Detalles Bibliográficos
Autores principales: Sundell, Gustav N, Arnold, Roland, Ali, Muhammad, Naksukpaiboon, Piangfan, Orts, Julien, Güntert, Peter, Chi, Celestine N, Ivarsson, Ylva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100724/
https://www.ncbi.nlm.nih.gov/pubmed/30126976
http://dx.doi.org/10.15252/msb.20178129