PKCα integrates spatiotemporally distinct Ca(2+) and autocrine BDNF signaling to facilitate synaptic plasticity

The Protein Kinase C (PKC) enzymes have long been established as critical for synaptic plasticity. However, it is unknown whether Ca(2+)-dependent PKC isozymes are activated in dendritic spines during plasticity, and if so, how this synaptic activity is encoded by PKC. Here, using newly-developed, i...

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Detalles Bibliográficos
Autores principales: Colgan, Lesley A, Hu, Mo, Misler, Jaime A, Parra-Bueno, Paula, Moran, Corey M, Leitges, Michael, Yasuda, Ryohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100743/
https://www.ncbi.nlm.nih.gov/pubmed/30013171
http://dx.doi.org/10.1038/s41593-018-0184-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100743/
https://www.ncbi.nlm.nih.gov/pubmed/30013171
http://dx.doi.org/10.1038/s41593-018-0184-3

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