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Insertion element mediated mgrB disruption and presence of ISKpn28 in colistin-resistant Klebsiella pneumoniae isolates from Saudi Arabia

BACKGROUND: In Klebsiella pneumoniae, mgrB and components of pmrHFIJKLM operon play a major role in colistin resistance. METHODS: We analyzed 23 nonduplicating colistin-resistant K. pneumoniae isolates, collected during the years 2011–2015, for the possible mechanism underlying their nonsusceptibili...

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Detalles Bibliográficos
Autores principales: Uz Zaman, Taher, Albladi, Maha, Siddique, Mohammed Ismail, Aljohani, Sameera M, Balkhy, Hanan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101004/
https://www.ncbi.nlm.nih.gov/pubmed/30147346
http://dx.doi.org/10.2147/IDR.S161146