Profile of intravenous glyburide for the prevention of cerebral edema following large hemispheric infarction: evidence to date

Glyburide (also known as glibenclamide) is a second-generation sulfonylurea drug that inhibits sulfonylurea receptor 1 (Sur1) at nanomolar concentrations. Long used to target K(ATP) (Sur1–Kir6.2) channels for the treatment of diabetes mellitus type 2, glyburide was recently repurposed to target Sur1...

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Detalles Bibliográficos
Autores principales: King, Zachary A, Sheth, Kevin N, Kimberly, W Taylor, Simard, J Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101021/
https://www.ncbi.nlm.nih.gov/pubmed/30147301
http://dx.doi.org/10.2147/DDDT.S150043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101021/
https://www.ncbi.nlm.nih.gov/pubmed/30147301
http://dx.doi.org/10.2147/DDDT.S150043

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