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Low-dose eribulin mesylate exerts antitumor effects in gastric cancer by inhibiting fibrosis via the suppression of epithelial–mesenchymal transition and acts synergistically with 5-fluorouracil

BACKGROUND: Characterized by aggressive proliferation, extensive stromal fibrosis, and resulting drug resistance, peritoneal dissemination in gastric cancer remains associated with poor prognosis. Interaction between cancer and stromal cells accelerates tumor progression via epithelial–mesenchymal t...

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Detalles Bibliográficos
Autores principales: Kurata, Toru, Fushida, Sachio, Kinoshita, Jun, Oyama, Katsunobu, Yamaguchi, Takahisa, Okazaki, Mitsuyoshi, Miyashita, Tomoharu, Tajima, Hidehiro, Ninomiya, Itasu, Ohta, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101023/
https://www.ncbi.nlm.nih.gov/pubmed/30147370
http://dx.doi.org/10.2147/CMAR.S167846