The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation

The RAF/MEK/ERK cascade is a conserved intracellular signaling pathway that controls fundamental cellular processes including growth, proliferation, differentiation, survival and migration. Aberrant regulation of this signaling pathway has long been associated with human cancers. A major point of re...

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Detalles Bibliográficos
Autores principales: Schneider, Taiane, Martinez-Martinez, Arturo, Cubillos-Rojas, Monica, Bartrons, Ramon, Ventura, Francesc, Rosa, Jose Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101136/
https://www.ncbi.nlm.nih.gov/pubmed/30140388
http://dx.doi.org/10.18632/oncotarget.25847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101136/
https://www.ncbi.nlm.nih.gov/pubmed/30140388
http://dx.doi.org/10.18632/oncotarget.25847

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