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Combination of electroporation delivered metabolic modulators with low-dose chemotherapy in osteosarcoma

BACKGROUND: Osteosarcoma accounts for roughly 60% of all malignant bone tumors in children and young adults. The five-year survival rate for localized tumors after surgery and chemotherapy is approximately 70% whilst it drastically reduces to 15–30% in metastatic cases. Metabolic modulation is known...

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Detalles Bibliográficos
Autores principales: Gill, Kheshwant S., Fernandes, Philana, Bird, Brian, Soden, Declan M., Forde, Patrick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101145/
https://www.ncbi.nlm.nih.gov/pubmed/30140384
http://dx.doi.org/10.18632/oncotarget.25843