Relevance of methylenetetrahydrofolate reductase gene variants C677T and A1298C with response to fluoropyrimidine-based chemotherapy in colorectal cancer: a systematic review and meta-analysis

Methylenetetrahydrofolate reductase (MTHFR) is a critical enzyme influencing the metabolism of fluoropyrimidines. The relevance of MTHFR polymorphisms with the clinical response to fluoropyrimidine-based chemotherapy has been explored, but the results remain controversial. Thus, a meta-analysis was...

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Detalles Bibliográficos
Autores principales: Zhong, Lei, He, Xia, Zhang, Yuan, Chuan, Jun-Lan, Chen, Min, Zhu, Shao-Min, Peng, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Meta-Analysis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101282/
https://www.ncbi.nlm.nih.gov/pubmed/30131855
http://dx.doi.org/10.18632/oncotarget.24933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101282/
https://www.ncbi.nlm.nih.gov/pubmed/30131855
http://dx.doi.org/10.18632/oncotarget.24933

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