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Cyclopeptide COR-1 to treat beta1-adrenergic receptor antibody-induced heart failure
RATIONALE: Despite advances in pharmacotherapy, heart failure still incurs significant morbidity and mortality. Stimulating antibodies directed against the secondextracellular loop of the human ß(1)-adrenergic receptor (anti-ß(1)EC2) cause myocyte damage and heart failure in rats. This receptor doma...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101361/ https://www.ncbi.nlm.nih.gov/pubmed/30125285 http://dx.doi.org/10.1371/journal.pone.0201160 |