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Association of crumbs homolog-2 with mTORC1 in developing podocyte

The evidence that gene mutations in the polarity determinant Crumbs homologs-2 (CRB2) cause congenital nephrotic syndrome suggests the functional importance of this gene product in podocyte development. Because another isoform, CRB3, was reported to repress the mechanistic/mammalian target of the ra...

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Detalles Bibliográficos
Autores principales: Hamano, Sho, Nishibori, Yukino, Hada, Ichiro, Mikami, Naoaki, Ito-Nitta, Noriko, Fukuhara, Daisuke, Kudo, Akihiko, Xiao, Zhijie, Nukui, Masatoshi, Patrakka, Jaakko, Tryggvason, Karl, Yan, Kunimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101391/
https://www.ncbi.nlm.nih.gov/pubmed/30125302
http://dx.doi.org/10.1371/journal.pone.0202400