Heterochromatin and RNAi regulate centromeres by protecting CENP-A from ubiquitin-mediated degradation

Centromere is a specialized chromatin domain that plays a vital role in chromosome segregation. In most eukaryotes, centromere is surrounded by the epigenetically distinct heterochromatin domain. Heterochromatin has been shown to contribute to centromere function, but the precise role of heterochrom...

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Detalles Bibliográficos
Autores principales: Yang, Jinpu, Sun, Siyu, Zhang, Shu, Gonzalez, Marlyn, Dong, Qianhua, Chi, Zhongxuan, Chen, Yu-hang, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101405/
https://www.ncbi.nlm.nih.gov/pubmed/30089114
http://dx.doi.org/10.1371/journal.pgen.1007572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101405/
https://www.ncbi.nlm.nih.gov/pubmed/30089114
http://dx.doi.org/10.1371/journal.pgen.1007572

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