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Heterochromatin and RNAi regulate centromeres by protecting CENP-A from ubiquitin-mediated degradation
Centromere is a specialized chromatin domain that plays a vital role in chromosome segregation. In most eukaryotes, centromere is surrounded by the epigenetically distinct heterochromatin domain. Heterochromatin has been shown to contribute to centromere function, but the precise role of heterochrom...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101405/ https://www.ncbi.nlm.nih.gov/pubmed/30089114 http://dx.doi.org/10.1371/journal.pgen.1007572 |