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Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines
Multiple enhancers often regulate a given gene, yet for most genes, it remains unclear which enhancers are necessary for gene expression, and how these enhancers combine to produce a transcriptional response. As millions of enhancers have been identified, high-throughput tools are needed to determin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MyJove Corporation
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101477/ https://www.ncbi.nlm.nih.gov/pubmed/29912188 http://dx.doi.org/10.3791/57883 |