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The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp

RNA polymerase (RNAP) contains a mobile structural module, the ‘clamp,’ that forms one wall of the RNAP active-center cleft and that has been linked to crucial aspects of the transcription cycle, including promoter melting, transcription elongation complex stability, transcription pausing, and trans...

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Detalles Bibliográficos
Autores principales: Duchi, Diego, Mazumder, Abhishek, Malinen, Anssi M, Ebright, Richard H, Kapanidis, Achillefs N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101503/
https://www.ncbi.nlm.nih.gov/pubmed/29878276
http://dx.doi.org/10.1093/nar/gky482