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The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp
RNA polymerase (RNAP) contains a mobile structural module, the ‘clamp,’ that forms one wall of the RNAP active-center cleft and that has been linked to crucial aspects of the transcription cycle, including promoter melting, transcription elongation complex stability, transcription pausing, and trans...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101503/ https://www.ncbi.nlm.nih.gov/pubmed/29878276 http://dx.doi.org/10.1093/nar/gky482 |