Cargando…
The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp
RNA polymerase (RNAP) contains a mobile structural module, the ‘clamp,’ that forms one wall of the RNAP active-center cleft and that has been linked to crucial aspects of the transcription cycle, including promoter melting, transcription elongation complex stability, transcription pausing, and trans...
Autores principales: | Duchi, Diego, Mazumder, Abhishek, Malinen, Anssi M, Ebright, Richard H, Kapanidis, Achillefs N |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101503/ https://www.ncbi.nlm.nih.gov/pubmed/29878276 http://dx.doi.org/10.1093/nar/gky482 |
Ejemplares similares
-
RNA polymerase clamp conformational dynamics: long-lived states and modulation by crowding, cations, and nonspecific DNA binding
por: Mazumder, Abhishek, et al.
Publicado: (2021) -
RNA polymerase redistribution supports growth in E. coli strains with a minimal number of rRNA operons
por: Fan, Jun, et al.
Publicado: (2023) -
Active site opening and closure control translocation of multisubunit RNA polymerase
por: Malinen, Anssi M., et al.
Publicado: (2012) -
Oxazinomycin arrests RNA polymerase at the polythymidine sequences
por: Prajapati, Ranjit K, et al.
Publicado: (2019) -
Substrate conformational dynamics facilitate structure-specific recognition of gapped DNA by DNA polymerase
por: Craggs, Timothy D, et al.
Publicado: (2019)