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Transitions in DNA polymerase β μs-ms dynamics related to substrate binding and catalysis
DNA polymerase β (pol β) plays a central role in the DNA base excision repair pathway and also serves as an important model polymerase. Dynamic characterization of pol β from methyl-TROSY (13)C-(1)H multiple quantum CPMG relaxation dispersion experiments of Ile and Met sidechains and previous backbo...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101544/ https://www.ncbi.nlm.nih.gov/pubmed/29917149 http://dx.doi.org/10.1093/nar/gky503 |