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SHAPE probing pictures Mg(2+)-dependent folding of small self-cleaving ribozymes

Self-cleaving ribozymes are biologically relevant RNA molecules which catalyze site-specific cleavage of the phosphodiester backbone. Gathering knowledge of their three-dimensional structures is critical toward an in-depth understanding of their function and chemical mechanism. Equally important is...

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Detalles Bibliográficos
Autores principales: Gasser, Catherina, Gebetsberger, Jennifer, Gebetsberger, Manuel, Micura, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101554/
https://www.ncbi.nlm.nih.gov/pubmed/29924364
http://dx.doi.org/10.1093/nar/gky555