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The Psychiatric Risk Gene Transcription Factor 4 (TCF4) Regulates Neurodevelopmental Pathways Associated With Schizophrenia, Autism, and Intellectual Disability

BACKGROUND: Common genetic variants in and around the gene encoding transcription factor 4 (TCF4) are associated with an increased risk of schizophrenia. Conversely, rare damaging TCF4 mutations cause Pitt–Hopkins syndrome and have also been found in individuals with intellectual disability (ID) and...

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Detalles Bibliográficos
Autores principales: Forrest, Marc P, Hill, Matthew J, Kavanagh, David H, Tansey, Katherine E, Waite, Adrian J, Blake, Derek J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101561/
https://www.ncbi.nlm.nih.gov/pubmed/29228394
http://dx.doi.org/10.1093/schbul/sbx164