N-terminal domain of human uracil DNA glycosylase (hUNG2) promotes targeting to uracil sites adjacent to ssDNA–dsDNA junctions

The N-terminal domain (NTD) of nuclear human uracil DNA glycosylase (hUNG2) assists in targeting hUNG2 to replication forks through specific interactions with replication protein A (RPA). Here, we explored hUNG2 activity in the presence and absence of RPA using substrates with ssDNA–dsDNA junctions...

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Detalles Bibliográficos
Autores principales: Weiser, Brian P, Rodriguez, Gaddiel, Cole, Philip A, Stivers, James T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101581/
https://www.ncbi.nlm.nih.gov/pubmed/29917162
http://dx.doi.org/10.1093/nar/gky525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101581/
https://www.ncbi.nlm.nih.gov/pubmed/29917162
http://dx.doi.org/10.1093/nar/gky525

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