A pipeline for computational design of novel RNA-like topologies

Designing novel RNA topologies is a challenge, with important therapeutic and industrial applications. We describe a computational pipeline for design of novel RNA topologies based on our coarse-grained RNA-As-Graphs (RAG) framework. RAG represents RNA structures as tree graphs and describes RNA sec...

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Detalles Bibliográficos
Autores principales: Jain, Swati, Laederach, Alain, Ramos, Silvia B V, Schlick, Tamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101589/
https://www.ncbi.nlm.nih.gov/pubmed/30137633
http://dx.doi.org/10.1093/nar/gky524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101589/
https://www.ncbi.nlm.nih.gov/pubmed/30137633
http://dx.doi.org/10.1093/nar/gky524

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