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A pipeline for computational design of novel RNA-like topologies
Designing novel RNA topologies is a challenge, with important therapeutic and industrial applications. We describe a computational pipeline for design of novel RNA topologies based on our coarse-grained RNA-As-Graphs (RAG) framework. RAG represents RNA structures as tree graphs and describes RNA sec...
Autores principales: | Jain, Swati, Laederach, Alain, Ramos, Silvia B V, Schlick, Tamar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101589/ https://www.ncbi.nlm.nih.gov/pubmed/30137633 http://dx.doi.org/10.1093/nar/gky524 |
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