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Autophagy-dependent ribosomal RNA degradation is essential for maintaining nucleotide homeostasis during C. elegans development

Ribosome degradation through the autophagy-lysosome pathway is crucial for cell survival during nutrient starvation, but whether it occurs under normal growth conditions and contributes to animal physiology remains unaddressed. In this study, we identified RNST-2, a C. elegans T2 family endoribonucl...

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Detalles Bibliográficos
Autores principales: Liu, Yubing, Zou, Wei, Yang, Peiguo, Wang, Li, Ma, Yan, Zhang, Hong, Wang, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101943/
https://www.ncbi.nlm.nih.gov/pubmed/30102152
http://dx.doi.org/10.7554/eLife.36588