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CNPY2 is a Key Initiator of the PERK-CHOP Pathway of the Unfolded Protein Response
The unfolded protein response (UPR) in the endoplasmic reticulum (ER) is a highly conserved protein quality control mechanism critical for cells to make survival-or-death decisions under ER stress conditions. However, how UPR sensors are activated remains unclear. Here, we report that ER luminal pro...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102046/ https://www.ncbi.nlm.nih.gov/pubmed/28869608 http://dx.doi.org/10.1038/nsmb.3458 |