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Structural insight into the human mitochondrial tRNA purine N1-methyltransferase and ribonuclease P complexes

Mitochondrial tRNAs are transcribed as long polycistronic transcripts of precursor tRNAs and undergo posttranscriptional modifications such as endonucleolytic processing and methylation required for their correct structure and function. Among them, 5′-end processing and purine 9 N1-methylation of mi...

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Detalles Bibliográficos
Autores principales: Oerum, Stephanie, Roovers, Martine, Rambo, Robert P., Kopec, Jola, Bailey, Henry J., Fitzpatrick, Fiona, Newman, Joseph A., Newman, William G., Amberger, Albert, Zschocke, Johannes, Droogmans, Louis, Oppermann, Udo, Yue, Wyatt W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102140/
https://www.ncbi.nlm.nih.gov/pubmed/29880640
http://dx.doi.org/10.1074/jbc.RA117.001286