Development of Bacillus methanolicus methanol dehydrogenase with improved formaldehyde reduction activity

Methanol dehydrogenase (MDH), an NAD(+)-dependent oxidoreductase, reversibly converts formaldehyde to methanol. This activity is a key step for both toxic formaldehyde elimination and methanol production in bacterial methylotrophy. We mutated decameric Bacillus methanolicus MDH by directed evolution...

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Detalles Bibliográficos
Autores principales: Yi, Jiyeun, Lee, Jinhyuk, Sung, Bong Hyun, Kang, Du-Kyeong, Lim, GyuTae, Bae, Jung-Hoon, Lee, Seung-Goo, Kim, Sun Chang, Sohn, Jung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102214/
https://www.ncbi.nlm.nih.gov/pubmed/30127388
http://dx.doi.org/10.1038/s41598-018-31001-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102214/
https://www.ncbi.nlm.nih.gov/pubmed/30127388
http://dx.doi.org/10.1038/s41598-018-31001-8

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