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A proline switch explains kinetic heterogeneity in a coupled folding and binding reaction
The interactions of intrinsically disordered proteins (IDPs) with their molecular targets are essential for the regulation of many cellular processes. IDPs can perform their functions while disordered, and they may fold to structured conformations on binding. Here we show that the cis/trans isomeriz...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102232/ https://www.ncbi.nlm.nih.gov/pubmed/30127362 http://dx.doi.org/10.1038/s41467-018-05725-0 |