Physiological and Pathological Brain Activation in the Anesthetized Rat Produces Hemodynamic-Dependent Cortical Temperature Increases That Can Confound the BOLD fMRI Signal

Anesthetized rodent models are ubiquitous in pre-clinical neuroimaging studies. However, because the associated cerebral morphology and experimental methodology results in a profound negative brain-core temperature differential, cerebral temperature changes during functional activation are likely to...

Descripción completa

Detalles Bibliográficos
Autores principales: Harris, Samuel S., Boorman, Luke W., Das, Devashish, Kennerley, Aneurin J., Sharp, Paul S., Martin, Chris, Redgrave, Peter, Schwartz, Theodore H., Berwick, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102348/
https://www.ncbi.nlm.nih.gov/pubmed/30154690
http://dx.doi.org/10.3389/fnins.2018.00550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102348/
https://www.ncbi.nlm.nih.gov/pubmed/30154690
http://dx.doi.org/10.3389/fnins.2018.00550

Ejemplares similares