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The Deconstructed Granuloma: A Complex High-Throughput Drug Screening Platform for the Discovery of Host-Directed Therapeutics Against Tuberculosis

Mycobacterium tuberculosis (Mtb) continues to be a threat to Global Public Health, and its control will require an array of therapeutic strategies. It has been appreciated that high-throughput screens using cell-based assays to identify compounds targeting Mtb within macrophages represent a valuable...

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Detalles Bibliográficos
Autores principales: Huang, Lu, Kushner, Nicole L., Theriault, Monique E., Pisu, Davide, Tan, Shumin, McNamara, Case W., Petrassi, H. Mike, Russell, David G., Brown, Amanda C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102409/
https://www.ncbi.nlm.nih.gov/pubmed/30155446
http://dx.doi.org/10.3389/fcimb.2018.00275