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Alterations of methionine metabolism in hepatocarcinogenesis: the emergent role of glycine N-methyltransferase in liver injury

The methionine and folate cycles play a fundamental role in cell physiology and their alteration is involved in liver injury and hepatocarcinogenesis. Glycine N-methyltransferase is implicated in methyl group supply, DNA methylation, and nucleotide biosynthesis. It regulates the cellular S-adenosylm...

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Detalles Bibliográficos
Autores principales: Simile, Maria M., Latte, Gavinella, Feo, Claudio F., Feo, Francesco, Calvisi, Diego F., Pascale, Rosa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hellenic Society of Gastroenterology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102450/
https://www.ncbi.nlm.nih.gov/pubmed/30174391
http://dx.doi.org/10.20524/aog.2018.0288