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Alterations of methionine metabolism in hepatocarcinogenesis: the emergent role of glycine N-methyltransferase in liver injury
The methionine and folate cycles play a fundamental role in cell physiology and their alteration is involved in liver injury and hepatocarcinogenesis. Glycine N-methyltransferase is implicated in methyl group supply, DNA methylation, and nucleotide biosynthesis. It regulates the cellular S-adenosylm...
Autores principales: | Simile, Maria M., Latte, Gavinella, Feo, Claudio F., Feo, Francesco, Calvisi, Diego F., Pascale, Rosa M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hellenic Society of Gastroenterology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102450/ https://www.ncbi.nlm.nih.gov/pubmed/30174391 http://dx.doi.org/10.20524/aog.2018.0288 |
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