Discovery of Pyrazolo[4,3-c]quinolines Derivatives as Potential Anti-Inflammatory Agents through Inhibiting of NO Production

The synthesis and anti-inflammatory effects of certain pyrazolo[4,3-c]quinoline derivatives 2a–2r are described. The anti-inflammatory activities of these derivatives were evaluated by means of inhibiting nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264.7 cells. Among them, 3...

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Detalles Bibliográficos
Autores principales: Tseng, Chih-Hua, Tung, Chun-Wei, Peng, Shin-I, Chen, Yeh-Long, Tzeng, Cherng-Chyi, Cheng, Chih-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102577/
https://www.ncbi.nlm.nih.gov/pubmed/29710774
http://dx.doi.org/10.3390/molecules23051036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102577/
https://www.ncbi.nlm.nih.gov/pubmed/29710774
http://dx.doi.org/10.3390/molecules23051036

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