Synthesis and Biological Evaluation of Azamacrolide Comprising the Triazole Moiety as Quorum Sensing Inhibitors

Novel azamacrolides comprising the triazole moiety were synthesized and evaluated for their quorum sensing inhibitor activities on the Agrobacterium tumefaciens. It was found that the inhibition rate of compound Z12-3 at 200 mg/L (0.45 mM) can reach 67%. The potential binding modes between these mol...

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Detalles Bibliográficos
Autores principales: Zhang, Bin, Guo, Bingyi, Bai, Yunlong, Lu, Huizhe, Dong, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102594/
https://www.ncbi.nlm.nih.gov/pubmed/29734673
http://dx.doi.org/10.3390/molecules23051086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102594/
https://www.ncbi.nlm.nih.gov/pubmed/29734673
http://dx.doi.org/10.3390/molecules23051086

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