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Neutralizing TGF-β promotes anti-tumor immunity of dendritic cells against pancreatic cancer by regulating T lymphocytes

Previous fundamental or clinical trials of dendritic cell (DC) vaccine against pancreatic ductal adenocarcinoma (PDAC) revealed the burgeoning neoadjuvant immunotherapy. Microarray studies indicated that multiple ingredients of the transfer growth factor beta (TGF-β) pathway were overexpressed in PD...

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Detalles Bibliográficos
Autores principales: Pu, Ning, Zhao, Guochao, Gao, Shanshan, Cui, Yutong, Xu, Yadong, Lv, Yang, Nuerxiati, Abulimiti, Wu, Wenchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Polish Society of Experimental and Clinical Immunology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102619/
https://www.ncbi.nlm.nih.gov/pubmed/30135623
http://dx.doi.org/10.5114/ceji.2018.77381