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Ginkgolide K protects SH-SY5Y cells against oxygen-glucose deprivation-induced injury by inhibiting the p38 and JNK signaling pathways

The purpose of the present study was to explore the protective effect and functional mechanism of ginkgolide K (GK: C(20)H(22)O(9)) on cerebral ischemia. SH-SY5Y cells were exposed to oxygen-glucose deprivation (OGD) to simulate an ischemic model in vitro. Cell viability, reactive oxygen species (RO...

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Detalles Bibliográficos
Autores principales: Liu, Qiu, Li, Xueke, Li, Liang, Xu, Zhiliang, Zhou, Jun, Xiao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102632/
https://www.ncbi.nlm.nih.gov/pubmed/30066915
http://dx.doi.org/10.3892/mmr.2018.9305