Oleuropein and rutin protect against 6-OHDA-induced neurotoxicity in PC12 cells through modulation of mitochondrial function and unfolded protein response

Parkinson’s disease (PD) is a highly prevalent neurodegenerative disorder, often associated with oxidative stress-induced transcriptional changes in dopaminergic neurons. Phenolic antioxidants, oleuropein (OLE) and rutin (RUT) have attracted a great interest due to their potential to counteract oxid...

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Detalles Bibliográficos
Autores principales: Elmazoglu, Zubeyir, Ergin, Volkan, Sahin, Ergin, Kayhan, Handan, Karasu, Cimen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102676/
https://www.ncbi.nlm.nih.gov/pubmed/30147420
http://dx.doi.org/10.1515/intox-2017-0019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102676/
https://www.ncbi.nlm.nih.gov/pubmed/30147420
http://dx.doi.org/10.1515/intox-2017-0019

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