NPM1 alternative transcripts are upregulated in acute myeloid and lymphoblastic leukemia and their expression level affects patient outcome

BACKGROUND: Expression of the NPM1 gene, encoding nucleophosmin, is upregulated in cancers. Although more than ten NPM1 transcripts are known, the reports were usually limited to one predominant transcript. In leukemia, the NPM1 expression has not been widely studied so far. In acute myeloid leukemi...

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Detalles Bibliográficos
Autores principales: Handschuh, Luiza, Wojciechowski, Pawel, Kazmierczak, Maciej, Marcinkowska-Swojak, Malgorzata, Luczak, Magdalena, Lewandowski, Krzysztof, Komarnicki, Mieczyslaw, Blazewicz, Jacek, Figlerowicz, Marek, Kozlowski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102803/
https://www.ncbi.nlm.nih.gov/pubmed/30126426
http://dx.doi.org/10.1186/s12967-018-1608-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102803/
https://www.ncbi.nlm.nih.gov/pubmed/30126426
http://dx.doi.org/10.1186/s12967-018-1608-2

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