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PU.1 regulates Alzheimer’s disease-associated genes in primary human microglia
BACKGROUND: Microglia play critical roles in the brain during homeostasis and pathological conditions. Understanding the molecular events underpinning microglial functions and activation states will further enable us to target these cells for the treatment of neurological disorders. The transcriptio...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102813/ https://www.ncbi.nlm.nih.gov/pubmed/30124174 http://dx.doi.org/10.1186/s13024-018-0277-1 |