Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma

Glioblastoma (GB) is the most frequent primary brain tumor in adults with a dismal prognosis despite aggressive treatment including surgical resection, radiotherapy and chemotherapy with the alkylating agent temozolomide. Thus far, the successful implementation of the concept of targeted therapy whe...

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Detalles Bibliográficos
Autores principales: Ronellenfitsch, Michael W., Zeiner, Pia S., Mittelbronn, Michel, Urban, Hans, Pietsch, Torsten, Reuter, Dirk, Senft, Christian, Steinbach, Joachim P., Westphal, Manfred, Harter, Patrick N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102828/
https://www.ncbi.nlm.nih.gov/pubmed/30129426
http://dx.doi.org/10.1186/s40478-018-0583-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102828/
https://www.ncbi.nlm.nih.gov/pubmed/30129426
http://dx.doi.org/10.1186/s40478-018-0583-4

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