Design of peptide-containing N5-unmodified neutral flavins that catalyze aerobic oxygenations

Simulation of the monooxygenation function of flavoenzyme (Fl-Enz) has been long-studied with N5-modified cationic flavins (FlEt(+)), but never with N5-unmodified neutral flavins (Fl) despite the fact that Fl is genuinely equal to the active center of Fl-Enz. This is because of the greater lability...

Descripción completa

Detalles Bibliográficos
Autores principales: Arakawa, Yukihiro, Yamanomoto, Ken, Kita, Hazuki, Minagawa, Keiji, Tanaka, Masami, Haraguchi, Naoki, Itsuno, Shinichi, Imada, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102831/
https://www.ncbi.nlm.nih.gov/pubmed/30155226
http://dx.doi.org/10.1039/c7sc01933e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102831/
https://www.ncbi.nlm.nih.gov/pubmed/30155226
http://dx.doi.org/10.1039/c7sc01933e

Ejemplares similares