MBD2 regulates differentiation and function of Th17 cells in neutrophils- dominant asthma via HIF-1α

BACKGROUND: T helper 17 (Th17) cells have proven to be crucial in the pathogenesis of neutrophils-dominant asthma. Hypoxia inducible factor-1α (HIF-1α) is involved in allergic responses in asthma. Our previous studies indicated that Methtyl-CpG binding domain protein 2 (MBD2) expression was increase...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Li, Sun, Wen J., Jia, Ai J., Qiu, Lu L., Xiao, Bing, Mu, Lin, Li, Jian M., Zhang, Xiu F., Wei, Yan, Peng, Cong, Zhang, Dong S., Xiang, Xu D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102869/
https://www.ncbi.nlm.nih.gov/pubmed/30150897
http://dx.doi.org/10.1186/s12950-018-0191-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102869/
https://www.ncbi.nlm.nih.gov/pubmed/30150897
http://dx.doi.org/10.1186/s12950-018-0191-x

Ejemplares similares