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Malignant canine mammary epithelial cells shed exosomes containing differentially expressed microRNA that regulate oncogenic networks

BACKGROUND: Breast (mammary) cancers in human (BC) and canine (CMT) patients share clinical, pathological, and molecular similarities that suggest dogs may be a useful translational model. Many cancers, including BC, shed exosomes that contain microRNAs (miRs) into the microenvironment and circulati...

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Detalles Bibliográficos
Autores principales: Fish, Eric J., Irizarry, Kristopher J., DeInnocentes, Patricia, Ellis, Connor J., Prasad, Nripesh, Moss, Anthony G., Curt Bird, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102898/
https://www.ncbi.nlm.nih.gov/pubmed/30126376
http://dx.doi.org/10.1186/s12885-018-4750-6