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Expression of oxidized protein tyrosine phosphatase and γH2AX predicts poor survival of gastric carcinoma patients

BACKGROUND: Oxidative stress induces various intracellular damage, which might be correlated with tumorigenesis. Accumulated oxidative stresses might inactivate protein tyrosine phosphatase (PTP) by oxidizing it, and inducing the phosphorylation of H2AX (γH2AX) in response to DNA damage. METHODS: We...

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Detalles Bibliográficos
Autores principales: Hussein, Usama Khamis, Park, Ho Sung, Bae, Jun Sang, Kim, Kyoung Min, Chong, Yun Jo, Kim, Chan Young, Kwon, Keun Sang, Chung, Myoung Ja, Lee, Ho, Kang, Myoung Jae, Moon, Woo Sung, Jang, Kyu Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102926/
https://www.ncbi.nlm.nih.gov/pubmed/30126387
http://dx.doi.org/10.1186/s12885-018-4752-4