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Expression of oxidized protein tyrosine phosphatase and γH2AX predicts poor survival of gastric carcinoma patients
BACKGROUND: Oxidative stress induces various intracellular damage, which might be correlated with tumorigenesis. Accumulated oxidative stresses might inactivate protein tyrosine phosphatase (PTP) by oxidizing it, and inducing the phosphorylation of H2AX (γH2AX) in response to DNA damage. METHODS: We...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102926/ https://www.ncbi.nlm.nih.gov/pubmed/30126387 http://dx.doi.org/10.1186/s12885-018-4752-4 |