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Eliciting unnatural immune responses by activating cryptic epitopes in viral antigens

Antigenic variation in viral surface antigens is a strategy for escaping the host’s adaptive immunity, whereas regions with pivotal functions for infection are less subject to antigenic variability. We hypothesized that genetically invariable and immunologically dormant regions of a viral surface an...

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Detalles Bibliográficos
Autores principales: Lee, Young Jae, Yu, Ji Eun, Kim, Paul, Lee, Jeong-Yoon, Cheong, Yu Cheol, Lee, Yoon Jae, Chang, Jun, Seong, Baik Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103170/
https://www.ncbi.nlm.nih.gov/pubmed/29570395
http://dx.doi.org/10.1096/fj.201701024RRR