Novel Iron-Chelator DIBI Inhibits Staphylococcus aureus Growth, Suppresses Experimental MRSA Infection in Mice and Enhances the Activities of Diverse Antibiotics in vitro

DIBI, a purpose-designed hydroxypyridinone-containing iron-chelating antimicrobial polymer was studied for its anti-staphylococcal activities in vitro in comparison to deferiprone, the chemically related, small molecule hydroxypyridinone chelator. The sensitivities of 18 clinical isolates of Staphyl...

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Detalles Bibliográficos
Autores principales: Parquet, Maria del Carmen, Savage, Kimberley A., Allan, David S., Davidson, Ross J., Holbein, Bruce E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103240/
https://www.ncbi.nlm.nih.gov/pubmed/30154764
http://dx.doi.org/10.3389/fmicb.2018.01811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103240/
https://www.ncbi.nlm.nih.gov/pubmed/30154764
http://dx.doi.org/10.3389/fmicb.2018.01811

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