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Connexin-mimetic peptide Gap 27 decreases osteoclastic activity

BACKGROUND: Bone remodelling is dependent on the balance between bone resorbing osteoclasts and bone forming osteoblasts. We have shown previously that osteoclasts contain gap-junctional protein connexin-43 and that a commonly used gap-junctional inhibitor, heptanol, can inhibit osteoclastic bone re...

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Detalles Bibliográficos
Autores principales: Ilvesaro, Joanna, Tavi, Pasi, Tuukkanen, Juha
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC61034/
https://www.ncbi.nlm.nih.gov/pubmed/11747476
http://dx.doi.org/10.1186/1471-2474-2-10