Cargando…

Protein motion in the nucleus: from anomalous diffusion to weak interactions

Understanding how transcription factors (TFs) regulate mammalian gene expression in space and time is a central topic in biology. To activate a gene, a TF has first to diffuse in the available space of the nucleus until it reaches a target DNA sequence or protein (target site). This eventually resul...

Descripción completa

Detalles Bibliográficos
Autores principales: Woringer, Maxime, Darzacq, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103463/
https://www.ncbi.nlm.nih.gov/pubmed/30065106
http://dx.doi.org/10.1042/BST20170310