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Beyond the Warburg Effect: How Do Cancer Cells Regulate One-Carbon Metabolism?

Altered metabolism in cancer cells is critical for tumor growth. One of the most notable aspects of this metabolic reprogramming lies in one-carbon metabolism. Cells require one-carbon units for nucleotide synthesis, methylation reactions, and for the generation of reducing cofactors. Therefore, the...

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Detalles Bibliográficos
Autores principales: Rosenzweig, Adam, Blenis, John, Gomes, Ana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103474/
https://www.ncbi.nlm.nih.gov/pubmed/30159313
http://dx.doi.org/10.3389/fcell.2018.00090